Motif ID: TLX1..3_NFIC{dimer}.p2

Z-value: 2.801


Transcription factors associated with TLX1..3_NFIC{dimer}.p2:

Gene SymbolEntrez IDGene Name
TLX1 3195 T-cell leukemia homeobox 1
TLX3 30012 T-cell leukemia homeobox 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TLX1chr10_+_1028810500.638.3e-03Click!
TLX3chr5_+_1706688920.253.5e-01Click!


Activity profile for motif TLX1..3_NFIC{dimer}.p2.

activity profile for motif TLX1..3_NFIC{dimer}.p2


Sorted Z-values histogram for motif TLX1..3_NFIC{dimer}.p2

Sorted Z-values for motif TLX1..3_NFIC{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TLX1..3_NFIC{dimer}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr21_+_45699830 6.308 NM_030582
NM_130444
COL18A1

collagen, type XVIII, alpha 1

chr6_-_31853027 4.637 NM_025258
C6orf27
chromosome 6 open reading frame 27
chr5_+_38481392 4.153 NM_182801
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr11_+_74539679 3.974 NM_001145212
NM_007256
SLCO2B1

solute carrier organic anion transporter family, member 2B1

chrX_-_53327473 3.382 NM_015075
IQSEC2
IQ motif and Sec7 domain 2
chr11_-_71429747 3.377 NUMA1
nuclear mitotic apparatus protein 1
chr1_-_1840564 3.303 NM_178545
TMEM52
transmembrane protein 52
chr22_+_40093245 3.175 NM_001145398
TEF
thyrotrophic embryonic factor
chr9_+_135389698 3.162 NM_014694
ADAMTSL2
ADAMTS-like 2
chr3_+_46717826 3.126 NM_147196
TMIE
transmembrane inner ear
chr19_+_10258642 3.114 NM_001039132
NM_001544
NM_022377
ICAM4


intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)


chr15_+_72828235 2.905 NM_000761
CYP1A2
cytochrome P450, family 1, subfamily A, polypeptide 2
chr14_-_80934523 2.827 NM_033104
STON2
stonin 2
chr12_-_50871953 2.807 NM_001081492
NM_182507
KRT80

keratin 80

chrX_+_106057984 2.677 CLDN2
claudin 2
chr14_+_72773957 2.629 NM_173462
NDRG2
PAPLN
NDRG family member 2
papilin, proteoglycan-like sulfated glycoprotein
chr17_+_75507750 2.622


chr9_+_137694988 2.517 NM_001001676
LCN9
lipocalin 9
chr9_-_139183675 2.412


chr12_-_51514328 2.372 NM_175834
KRT79
keratin 79

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
2.11 1.60e-03 GO:0005578 proteinaceous extracellular matrix
1.87 1.92e-02 GO:0031012 extracellular matrix
1.77 7.40e-07 GO:0044421 extracellular region part
1.71 3.88e-04 GO:0005615 extracellular space
1.51 1.43e-03 GO:0031226 intrinsic to plasma membrane
1.49 4.56e-03 GO:0005887 integral to plasma membrane
1.46 2.78e-05 GO:0005576 extracellular region
1.44 2.07e-05 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
12.55 4.38e-02 GO:0009008 DNA-methyltransferase activity